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Method for predicting cervical lymph node metastasis of oral cancer and diagnostic kit used for the prediction
Method for predicting cervical lymph node metastasis of oral cancer and diagnostic kit used for the prediction
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机译:口腔癌颈淋巴结转移的预测方法及用于预测的诊断试剂盒
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摘要
A method for objectively predicting possibility of metastasis to a cervical lymph node in an early stage for an individual case diagnosed as an oral cavity cancer, and a diagnosis kit to be used in the prediction are provided. The method includes a step of assaying expression amounts of metastasis prediction genes in which the expression amounts are changed between a metastasis group and a non-metastasis group, with respect to a sample collected from a primary legion of the oral cavity cancer. Further, the method includes a step of predicting the possibility of the metastasis by comparing the expression amounts of the metastasis gene group with the expression amounts of the metastasis prediction genes in a metastasis group and/or a non-metastasis group. Herein, the metastasis prediction gene group includes two genes MSR1 (NM_138716.1) and RET (M31213.1).
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