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首页> 外国专利> DIFFERENTIAL DIAGNOSTIC TECHNIQUE FOR FORMS OF ACUTE INFLAMMATORY POLYNEUROPATHY AND CHRONIC INFLAMMATORY DEMYELINATING POLYNEUROPATHY WITH ACUTE ONSET

DIFFERENTIAL DIAGNOSTIC TECHNIQUE FOR FORMS OF ACUTE INFLAMMATORY POLYNEUROPATHY AND CHRONIC INFLAMMATORY DEMYELINATING POLYNEUROPATHY WITH ACUTE ONSET

机译：急性炎症性多发性神经病和慢性炎症性脱发性多发性神经病的鉴别诊断技术

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FIELD: medicine.;SUBSTANCE: invention refers to medicine, namely to neurology, infectious diseases, clinical immunology. It involves electric neuromyographic, clinical and clinical-biochemical examinations. If observing in the patient 6-9 of the 9 following signs: electric neuromyography showing signs of generalised primary axonal motor and sensory nerve disorder, age 46-60 years old, the presence of associated cardiovascular diseases, the absence of an indicated previous acute enteric infection, a level of haemoglobin less than 132 g/l, erythrocyte count 3.7*1012/l or less, alkaline phosphatase level more than 177 Un/l, CD 19+ lymphocytes count less than 0.19*109/l, IgA level more than 1.7 g/l, acute motor-sensor axonal neuropathy is diagnosed. If observing 4-9 of the 9 following signs: electric neuromyography showing signs of generalised, mainly motor, neural level of primary axonal disorder, age 60 years old and more, the presence of associated thyroid disease, the presence of a previous acute enteric infection one month ago and later, anti-GMI level 70 % and more, anti-GdIb level 90 % and more, a rheumatoid factor 5 IU/ml and more, IgE level less than 40 IU/ml, CD16+/CD56+ lymphocyte count 7 % and less, acute motor axonal neuropathy is diagnosed. If observing 2-4 of the 4 following signs: electric neuromyography showing signs of initially demyelinating process in peripheral nerves, IgM level more than 24 g/l, CD3+/HLA-DR+ lymphocyte count more than 2.0 %, IgE level more than 60 IU/ml, acute inflammatory demyelinating polyneuropathy is diagnosed. If observing 4-5 of the 5 following signs: anti-GM2 level 6 % and less, monocyte count more than 8.5 %, aspartate aminotransfrerase level 36 Un/l and less, IgA level 0.8 g/l less, detection of blood HSV type II IgM, chronic inflammatory demyelinating polyneuropathy with acute onset is diagnosed.;EFFECT: technique extends the range of products for differential diagnostics of forms of acute inflammatory polyneuropathy and chronic inflammatory demyelinating polyneuropathy with acute onset.;10 tbl, 4 ex
机译：技术领域：药物：发明是指医学，即神经病学，传染病，临床免疫学。它涉及电神经肌电图检查，临床和临床生化检查。如果在患者中观察到以下9种体征中的6-9：表现为广泛性原发性轴突运动和感觉神经障碍体征的电神经肌电图，年龄46-60岁，存在相关的心血管疾病，没有先前明确的急性肠溶性疾病感染，血红蛋白水平小于132 g / l，红细胞计数为3.7 * 10 12 / l以下，碱性磷酸酶水平大于177 Un / l，CD 19+淋巴细胞计数小于0.19 * 10 9 / l，IgA水平超过1.7 g / l，诊断为急性运动传感器轴突神经病。如果观察到以下9种征象中的4-9：电神经肌电图显示全身性征象，主要是运动性，原发性轴突疾病的神经水平，年龄60岁及以上，伴有甲状腺疾病，先前有急性肠道感染一个月之前和之后，抗GM I 水平达到70％以上，抗Gd Ib 水平达到90％以上，类风湿因子达到5 IU / ml以上， IgE水平低于40 IU / ml，CD16 + / CD56 +淋巴细胞计数低于7％，可诊断为急性运动性轴索神经病。如果观察到以下4种迹象中的2-4种：电神经肌电图显示周围神经开始出现脱髓鞘的迹象，IgM水平超过24 g / l，CD3 + / HLA-DR +淋巴细胞计数超过2.0％，IgE水平超过60 IU / ml，诊断为急性炎症性脱髓鞘性多神经病。如果观察到以下5个征兆中的4-5：抗GM 2 的水平小于或等于6％，单核细胞计数大于8.5％，天冬氨酸转氨酶的水平小于或等于36 Un / l，IgA的水平小于0.8 g /更少，诊断出血液II型HSV IgM，诊断为急性发作的慢性炎症性脱髓鞘性多发性神经病。;效果：该技术扩展了对急性发作性急性炎症性多发性神经病和慢性炎症性脱髓鞘性多发性神经病的鉴别诊断的产品范围。; 10 tbl，前4位

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