首页> 外国专利> METHOD OF PREDICTING RISK OF DIABETIC RETINOPATHY DEVELOPMENT IN CASE OF TYPE 2 DIABETES MELLITUS IN YAKUTS

METHOD OF PREDICTING RISK OF DIABETIC RETINOPATHY DEVELOPMENT IN CASE OF TYPE 2 DIABETES MELLITUS IN YAKUTS

机译:预测雅库特2型糖尿病患者糖尿病视网膜病变发展的风险的方法

摘要

FIELD: medicine.;SUBSTANCE: invention can be used for prediction of development and prevention of diabetic retinopathy (DR) in case of type 2 diabetes mellitus (DM type 2) in Yakuts. Method includes isolation of DNA from lymphocytes of peripheral venous blood, amplification of adiponektin (ADIPOQ) gene specificity being determined by method of polymerase chain reaction of DNA synthesis. If genotype *H/*H of polymorphic version Y111H ADIPOQ is detected, risk of diabetic retinopathy development is predicted.;EFFECT: application of invention makes it difficult to predict and detect DR risk groups among Yakuts in due time.;2 tbl
机译:领域:药物;发明:本发明可用于预测雅库特地区2型糖尿病(DM 2型)糖尿病视网膜病变(DR)的发生和预防。方法包括从外周静脉血的淋巴细胞中分离DNA,通过DNA合成的聚合酶链反应法确定脂联素(ADIPOQ)基因特异性的扩增。如果检测到多态性版本Y111H ADIPOQ的基因型* H / * H,则可以预测糖尿病性视网膜病发生的风险。效果:本发明的应用使得在雅库特地区难以及时预测和检测DR风险组。2tbl

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