METHOD increase the depth of the tympanic cavity in patients after radical operation on the middle ear BY AUTOHRYASCHEVYH PLATES

• 1. 一种中耳鼓膜贴补用补片辅助放置装置 [P] . 中国专利： CN213283777U . 2021-05-28
• 2. 用于操纵体管腔或体腔的侧壁以便提供体管腔和体腔的增加可视化和/或对体管腔或体腔的增加进入和/或用于使仪器相对于体管腔或体腔稳定的方法和设备 [P] . 中国专利： CN113038862A . 2021-06-25
• 3. METHOD FOR TYMPANIC CAVITY DEEPENING IN PATIENTS UNDERWENT RADICAL MIDDLE EAR SURGERY WITH USING AUTOCARTILAGE PLATE [P] . 俄罗斯专利： RU2526422C2 . 2014-08-20

  机译： 自体软骨板在根治性中耳外科手术患者中进行空洞去深度的方法

• 4. METHOD OF FORMING THE MUCOUS LINING OF NEOTYMPANIC CAVITY IN REPARATIVE OPERATION IN PATIENTS AFTER RADICAL OPERATION OF EAR [P] . 俄罗斯专利： RU2145829C1 . 2000-02-27

  机译： 耳根治术后患者修复手术中新腔粘膜形成的方法。

• 5. METHOD FOR RECONSTRUCTION OF "THE OLD RADICAL CAVITY" With tympanoplasty sanitize AFTER OPERATION OF THE OPEN TYPE middle ear [P] . 俄罗斯专利： RU2012156040A . 2014-06-27

  机译： 鼓室成形术重建“旧根管腔”的方法在开放式中耳手术后进行消毒

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• 2. Effects of different anesthesia depth on the level of plasma cortisol during operation and the score of postoperative MMSE in elderly patients with radical operation for gastric carcinoma [J] . Duo-Zhi Wu, Hai Xie, Jian Liu, 海南医科大学学报(英文版) . 2017,第009期
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• 1. BACKGROUND： Vibrio vulnifi cus inside the body could activate the NF-!B signaling pathwayand initiate the inflammatory cascade. The lung is one of the earliest organs affected by sepsisassociated with acute lung injury. High mobility group protein B1 （HMGB1） is an important late-actingpro-infl ammatory cytokine involving in the pathophysiology of sepsis. It is also involved in the injuryprocess in the lung, liver and intestine. There has been no report on the involvement of HMGB1 inVibrio vulnifi cus sepsis-induced lung injury.METHODS： Sixty rats were randomly divided into a normal control group （group A, n=10） anda Vibrio vulnificus sepsis group （group B, n=50）. Sepsis was induced in the rats by subcutaneousinjection of Vibrio vulnificus （concentration 6×108 cfu/mL, volume 0.1 mL/100g）） into the left lowerlimbs. The rats in group B were sacrifi ced separately 1, 6, 12, 24, and 48 hours after the infection.Their lungs were stored as specimens, lung water content was measured, and lung pathology wasobserved under a light microscope. The expressions of the HMGB1 gene and protein in the lungswere detected by RT-PCR and Western blot. Data were analyzed with one-way analysis of variance（ANOVA） and the LSD method for pair-wise comparison between the two groups. P〈0.05 wasconsidered statistically signifi cant.RESULTS： Compared to group A （0.652±0.177）, HMGB1 mRNA expression in the lungs ofgroup B was signifi cantly higher at 0 hour （1.161±0.358, P=0.013）, 24 hours （1.679±0.235, P=0.000）,and 48 hours （1.258±0.274, P=0.004） （P〈0.05）, and peaked at 24 hours. Compared to group A（0.594±0.190）, HMGB1 protein expression at 6 hours （1.408±0.567, P=0.026） after infection wassignificantly increased （P〈0. 05）, and peaked at 24 hours （2.415±1.064, P=0.000） after infection.Compared to group A （0.699±0.054）, lung water content was significantly increased at 6 hours（0.759±0.030, P=0.001）,12 hours （0.767±0.023, P=0.000）, 24 hours （0.771±0.043, P=0.000） and 48hours （0.789±0.137, P=0.000） after infection （P〈0.05）. Compared to group A, pathological changesat 12 hours in group B indicate marked pulmonary vascular congestion, interstitial edema andinfl ammatory infi ltration. Alveolar cavity collapse and boundaries of the alveolar septum could not beclearly identifi ed.CONCLUSION： Vibrio vulnifi cus sepsis can lead to injury in rat lungs, and increased HMGB1expression in lung tissue may be one of the mechanisms for injury from Vibrio vulnifi cus sepsis. [J] . Qiao-meng Qiu ,Zhong-wang Li ,Lu-ming Tang . 世界急诊医学杂志(英文) . 2011,第4期
• 2. 不同方法联合应用于左双腔支气管导管定位和插管深度对患者侧卧位后左双腔支气管导管错位的影响 [C] . 赵楠 . 天津医学会麻醉学分会2011年度学术年会 . 2012
• 3. 中耳压力平衡试验评估COME患者咽鼓管功能和预测鼓膜置管术后复发的研究 [A] . 张凌雪 . 2018