首页> 外国专利> The method for preparing patterned protein nanoarrays with enhanced protein adsorption on a self-assembled block copolymer thin film and the patterned protein nanoarrays thereby

The method for preparing patterned protein nanoarrays with enhanced protein adsorption on a self-assembled block copolymer thin film and the patterned protein nanoarrays thereby

机译:自组装嵌段共聚物薄膜上蛋白质吸附增强的图案化蛋白质纳米阵列的制备方法及图案化蛋白质纳米阵列

摘要

The present invention provides an improved method of producing a protein adsorbed protein nano-array block copolymer self-assembly is disposed on the foil and accordingly relates to a protein produced nano-arrays, and more particularly, by using a self-assembly properties of the block copolymer was prepared in the template of the nano-array form, the linear density of a control surface interface of the two polymers of the block copolymer to the template manufacture, and this pattern will optionally including the step of attaching the protein on the template being formed according to the production method and hence the protein nano-arrays manufactured in accordance with the adsorption of protein-enhanced protein nano-arrays. The improved method for producing a protein adsorbed protein nano-array according to the present invention is able to selectively adsorb the protein to the self-assembled block copolymer became easy to improve the conventional protein immobilization method, two of the block copolymer on the template By controlling the linear density of the surface interface of the polymer to improve the adsorption of protein may provide an improved effect as a protein sensor.
机译:本发明提供了一种改进的生产蛋白质吸附的蛋白质纳米阵列嵌段共聚物的自组装方法,该方法将自组装置于箔上,并因此涉及一种蛋白质生产的纳米阵列,更具体地讲,是通过利用其的自组装特性以纳米阵列形式的模板制备嵌段共聚物,该嵌段共聚物的两种聚合物的控制表面界面的线性密度与模板制备,并且该图案将任选地包括将蛋白质附着在模板上的步骤根据生产方法形成蛋白质纳米阵列,并因此根据蛋白质增强的蛋白质纳米阵列的吸附来制造蛋白质纳米阵列。根据本发明的用于生产蛋白质吸附的蛋白质纳米阵列的改进方法能够将蛋白质选择性地吸附到自组装的嵌段共聚物上,变得易于改进常规的蛋白质固定方法,将两种嵌段共聚物放在模板上控制聚合物的表面界面的线密度以改善蛋白质的吸附可以提供作为蛋白质传感器的改善的效果。

著录项

  • 公开/公告号KR101018414B1

    专利类型

  • 公开/公告日2011-02-28

    原文格式PDF

  • 申请/专利权人

    申请/专利号KR20080074493

  • 发明设计人 김동하;

    申请日2008-07-30

  • 分类号G01N33/68;G01N33/53;G01N33/48;

  • 国家 KR

  • 入库时间 2022-08-21 17:50:30

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