首页>
外国专利>
Method for detecting methylation of gastric cancer specific methylation marker gene for gastric cancer diagnosis
Method for detecting methylation of gastric cancer specific methylation marker gene for gastric cancer diagnosis
展开▼
机译:检测用于胃癌诊断的胃癌特异性甲基化标记基因甲基化的方法
展开▼
页面导航
摘要
著录项
相似文献
摘要
PURPOSE: A method for detecting methylation of gastric cancer-specific methylated marker gene is provided to quickly and accurately diagnose gastric cancer. CONSTITUTION: A method for detecting methylation is PCR, methylateion-specific PCR, real time methylation-specific PCR, PCR using methylation DNA-specific binding protein, quantitative PCR, pyrosequencing or bisulfite sequencing. A promoter is a sequence of sequence number 1. A kit for diagnosing gastric cancer or progression of the cancer comprises: primer pair for amplifying a gastric cancer specific-methylation marker gene COL24A1(NM_152890, collagen type 24, alpha 1) promoter CpG island; and methylation-sensitive restriction endonuclease. The endonuclease is SmaI, HpaII, BssHII, BstUI, NotI, SacII or EagI.
展开▼