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Method for large scale preparation of the active domain of human protein tyrosine phosphatase without fusion protein
Method for large scale preparation of the active domain of human protein tyrosine phosphatase without fusion protein
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机译:无融合蛋白的人蛋白酪氨酸磷酸酶活性域大规模制备方法
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摘要
invention protein tyrosine dephosphorylation enzyme (protein tyrosine phosphatase; hereinafter, PTP), and a method of manufacturing the same in It relates to, and specifically relates to the prediction method of the active PTP domain, capable of expressing the domain only fusion protein in a form having the activity and stability without. The PTP was prepared according to the process of the present invention can be used as a protein antigen protein for structural and functional studies and PTP for efficient drug discovery, drug development for selective antibody production.
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