首页> 外国专利> COMPOSITION FOR TREATMENT OF CANCER WHICH IS PRODUCED FROM CANCER-TISSUE-DERIVED CELL MASS OR CANCER CELL AGGREGATE, AND PROCESS FOR PRODUCTION OF IMMUNOTHERAPEUTIC AGENT AND METHOD FOR EVALUATION OF EFFICACY OF IMMUNOTHERAPY BOTH USING THE COMPOSITION

COMPOSITION FOR TREATMENT OF CANCER WHICH IS PRODUCED FROM CANCER-TISSUE-DERIVED CELL MASS OR CANCER CELL AGGREGATE, AND PROCESS FOR PRODUCTION OF IMMUNOTHERAPEUTIC AGENT AND METHOD FOR EVALUATION OF EFFICACY OF IMMUNOTHERAPY BOTH USING THE COMPOSITION

机译:由源自癌组织的细胞块或癌细胞聚集物产生的癌症的治疗组合物,免疫治疗剂的生产过程以及使用该组合物评估免疫治疗效果的方法

摘要

Disclosed are an immunotherapy and a method for evaluating the efficacy of an immunotherapy, both of which utilize a novel cancer-tissue-derived cell mass (a cell mass derived from a cancer tissue) or a novel cancer cell aggregate which can reflect the in vivo behavior of a cancer cell accurately. A composition for treating cancer is prepared by chemically or photodynamically treating a cancer-tissue-derived cell mass or a cancer cell aggregate. The composition for treating cancer can be used as a cancer vaccine which is intended to be directly administered to a patient from which the cell mass or the cell aggregate is derived, or as a medicinal agent which is intended to be contacted in vitro with cells derived from blood collected from the patient. Further, the efficacy of an immunotherapy can be evaluated by measuring the activity of a killer T-cell in blood over time using a cancer-tissue-derived cell mass or a cancer cell aggregate.
机译:公开了一种免疫疗法和评估免疫疗法的功效的方法,两者均利用可反映<I的新型癌症组织来源的细胞团(源自癌组织的细胞团)或新型癌细胞集合体。癌细胞的>体内行为。通过化学或光动力处理癌组织来源的细胞团或癌细胞聚集体来制备用于治疗癌症的组合物。用于治疗癌症的组合物可以用作旨在直接施用于细胞群或细胞聚集体来源的患者的癌症疫苗,或者用作旨在在体外接触的药物。 包含从患者血液中收集的细胞。此外,可以通过使用源自癌组织的细胞团或癌细胞聚集体随时间测量血液中的杀伤性T细胞的活性来评估免疫疗法的功效。

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