首页> 外国专利> USE OF COMPOUNDS WITH A 2-CYCLOPENTENONE STRUCTURE FOR THE INHIBITION OF ENZYMES OF THE FAMILY OF ALDO-KETO REDUCTASES

USE OF COMPOUNDS WITH A 2-CYCLOPENTENONE STRUCTURE FOR THE INHIBITION OF ENZYMES OF THE FAMILY OF ALDO-KETO REDUCTASES

机译:使用具有2-环戊烯酮结构的化合物抑制醛酮还原酶家族的酶

摘要

The invention relates to the use of a series of compounds having a 2-cyclopentenone nucleus substituted by alkyl and alkenyl chains that are proven inhibitors of aldo-keto reductase (AKR) enzymes, specifically AKR1 B1 and AKR1 B10. Consequently, the compounds of the invention can be used for the treatment of pathological conditions or diseases involving said enzymes.
机译:本发明涉及具有被烷基和烯基链取代的2-环戊烯酮核的一系列化合物的用途,这些化合物被证明是醛酮还原酶(AKR)酶,特别是AKR1B1和AKR1B10的抑制剂。因此,本发明的化合物可用于治疗涉及所述酶的病理状况或疾病。

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