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CD44 POLYMORPHISMS PREDICT CLINICAL OUTCOME IN PATIENTS WITH GASTRIC CANCER

机译:CD44多态性可预测胃癌患者的临床结果

摘要

This disclosure is directed to diagnostic and therapeutic methods for aiding in identifying a gastrointestinal cancer patient that will have a positive therapeutic response to therapy comprising the administration of 5-fluorouracil or an equivalent thereof, as compared to similarly situated patients. The method comprises determining a genotype of a cell or tissue sample isolated from the patient for selected polymorphisms in the CD44 gene.
机译:本公开涉及用于诊断胃肠道癌症患者的诊断和治疗方法,与处于类似位置的患者相比,所述胃肠道癌症患者将对包括施用5-氟尿嘧啶或其等效物的疗法具有积极的治疗反应。该方法包括确定针对CD44基因中选定的多态性而从患者分离的细胞或组织样品的基因型。

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