首页> 外国专利> DIFFERENTIAL EXPRESSION OF MICRORNAS IN NONFAILING VERSUS FAILING HUMAN HEARTS

DIFFERENTIAL EXPRESSION OF MICRORNAS IN NONFAILING VERSUS FAILING HUMAN HEARTS

机译:微小RNA在正常人对正常人心脏中的差异表达

摘要

The present invention discloses specific miRNAs as novel biomarkers and therapeutic targets in the treatment of heart failure. Methods of treating or preventing heart failure in a subject by administering mimics or inhibitors of these particular miRNAs are disclosed. A method of diagnosing or prognosing heart failure in a subject by determining the level of expression of one or more miRNAs is also described.
机译:本发明公开了特异性miRNA作为心力衰竭治疗中的新型生物标志物和治疗靶标。公开了通过施用这些特定miRNA的模拟物或抑制剂来治疗或预防受试者的心力衰竭的方法。还描述了一种通过确定一种或多种miRNA的表达水平来诊断或预后受试者心力衰竭的方法。

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