PEPTIDE DEFORMYLASE INHIBITOR CONTAINING 2,5-DIHYDROPYRROLE AND SYNTHESIS METHOD THEREOF
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机译：含有2，5-二氢吡咯的肽脱甲酰酶抑制剂及其合成方法
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摘要
A peptide deformylase inhibitor containing 2,5-dihydropyrrole, its synthesis method and its use as antibacterial agent are disclosed. The peptide deformylase inhibitor containing 2,5-dihydropyrrole has the structure as formula (A). Wherein R1 is alkyl; R2 is H or alkyl; and R3 is alkyl, aryl, or heterocyclic group. The synthesized peptide deformylase inhibitor can inhibit the protein synthesis of bacteria, and thus kill bacteria. The incidence of drug resistance is very low.
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机译：公开了一种含有2，5-二氢吡咯的肽去甲酰基酶抑制剂，其合成方法及其作为抗菌剂的用途。含有2，5-二氢吡咯的肽去甲酰基酶抑制剂具有式（A）的结构。其中R1为烷基; R 2是H或烷基; R 3为烷基，芳基或杂环基。合成的肽去甲酰基酶抑制剂可以抑制细菌的蛋白质合成，从而杀死细菌。耐药性的发生率很低。
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