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SAMPLING PROBE MICROARRAY READ OUT USING ELECTROSPRAY MASS SPECTROMETRY
SAMPLING PROBE MICROARRAY READ OUT USING ELECTROSPRAY MASS SPECTROMETRY
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机译：使用电喷雾质谱法对采样探针进行微阵列读取
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摘要
An automated electrospray based sampling system and method for analysisobtains samples from surface array spots having analytes. The system includesat least one probe, the probe including an inlet for flowing at least oneeluting solvent to respective ones of a plurality of spots and an outlet fordirecting the analyte away from the spots. An automatic positioning system isprovided for translating the probe relative to the spots to permit sampling ofany spot. An electrospray ion source having an input fluidicly connected tothe probe receives the analyte and generates ions from the analyte. The ionsource provides the generated ions to a structure for analysis to identify theanalyte, preferably being a mass spectrometer. The probe can be a surfacecontact probe, where the probe forms an enclosing seal along the periphery ofthe array spot surface.
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