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ANDROGEN RECEPTOR SUPPRESSORS IN THE THERAPY AND DIAGNOSIS OF PROSTATE CANCER, ALOPECIA AND OTHER HYPER-ANDROGENIC SYNDROMES
ANDROGEN RECEPTOR SUPPRESSORS IN THE THERAPY AND DIAGNOSIS OF PROSTATE CANCER, ALOPECIA AND OTHER HYPER-ANDROGENIC SYNDROMES
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机译:前列腺癌,恶性肿瘤和其他高雄激素综合症的治疗和诊断中的雄激素受体抑制剂
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摘要
Substituted phenylalanines are provided comprising an hydantoin, urea or 2-hydroxyl, 2-methylpropionyl group, dimers thereof and alkyl, polyfluoroamidoand haloarylamino derivatives thereof, as well as radiolabeled derivativesthereof. The compounds bind specifically to the androgen receptor and find usein indications associated with the androgen receptor, such as cell hyperplasiadependent on androgens, hirsutism, acne and androgenetic alopecia.
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