首页> 外国专利> Solid compositions comprising (2R, 6S, 13as 14ar 16aS,,, (Z) - N - (cyclopropylsulfonyl) - 6 - (5 - metilpirazin - 2 - 16 carboxamido) - 5 - 2 - (fenantridin - 6 - iloxi) - 1,2,3,5,6,7,8,9,10,11,13a, 14,14a, 15,16,16a - hexadecahidrociclopropa e pirrolo 1.2 - 1,4 diazaciclopentadecin - 14th - carboxamide to use co Mo inhibitors of HCV and Process for its preparation

Solid compositions comprising (2R, 6S, 13as 14ar 16aS,,, (Z) - N - (cyclopropylsulfonyl) - 6 - (5 - metilpirazin - 2 - 16 carboxamido) - 5 - 2 - (fenantridin - 6 - iloxi) - 1,2,3,5,6,7,8,9,10,11,13a, 14,14a, 15,16,16a - hexadecahidrociclopropa e pirrolo 1.2 - 1,4 diazaciclopentadecin - 14th - carboxamide to use co Mo inhibitors of HCV and Process for its preparation

机译：包含（2R，6S，13as 14ar 16aS ,,（Z）-N-（环丙基磺酰基）-6-（5-甲丙哌嗪-2-16甲酰胺基）-5-[2-（fenantridin-6-伊洛西）- 1,2,3,5,6,7,8,9,10,11,13a，14,14a，15,16,16a-十六碳十二烷[e] [吡咯罗1.2-] [1,4]二氮杂泛酸-14th-羧酰胺使用丙肝病毒的钴钼抑制剂及其制备方法

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摘要

Solid compositions comprising the compounds i Amorphous. A Solid dispersion of the present Invention also contains a Hydrophilic Polymer and a pharmaceutically acceptable pharmaceutically acceptable surfactant.Compound I can be formulated in a Solid Amorphous dispersion comprising a Hydrophilic Polymer and preferably a pharmaceutically acceptable pharmaceutically acceptable surfactant.

机译：包含化合物i无定形的固体组合物。本发明的固体分散体还包含亲水性聚合物和药学上可接受的药学上可接受的表面活性剂。化合物I可以配制成包含亲水性聚合物和优选药学上可接受的药学上可接受的表面活性剂的固体无定形分散体。

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公开/公告号UY33265A

专利类型
公开/公告日2011-10-31

原文格式PDF
申请/专利权人 ABBOTT LABORATORIES;ENANTA PHARMACEUTICALS INC.;
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申请/专利号UY20110033265
发明设计人 LIEPOLD BERND;ROSENBLATT KARIN;HOELIG PETER;GOKHALE RAJEEV;PRASAD LEENA;MILLER JONATHAN;MORRIS JOHN B.;
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申请日2011-03-09
分类号A61P31/12;C07D487/04;
国家 UY
入库时间 2022-08-21 18:04:22

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