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(R-BENZOLOXAMIDO)BUTANOIC ACIDS EXHIBITING DIURETIC, ANTI-INFLAMMATORY AND ANALGETIC ACTIVITY

机译：（R-苯甲酰氨基）丁酸具有利尿，消炎和镇痛作用

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摘要

The invention relates to chemico-pharmaceutical industry, in particular to the synthesis of bioactive chemical compounds of butanoic acid amide series, and can be used as drug substances in the production of pharmaceutical preparations with diuretic, anti-inflammatory and analgetic activity.The object of the invention is to provide (R-benzoloxamido)butanoic acids of formula:RCHNHCOCONH(CH)COOH,wherein R = 2-CHor OCH, or 3-COOH, or 2-COOCH, or 3-COOCH, or 2-COOCH,exhibiting diuretic, anti-inflammatory and analgetic activity.

机译：本发明涉及化学制药工业，尤其涉及丁酸酰胺系列生物活性化合物的合成，可用作生产具有利尿，抗炎和镇痛作用的药物制剂的药物。本发明提供了式：RCHNHCOCONH（CH）COOH的（R-苯并氧杂酰胺）丁酸，其中R ＝ 2-CH或OCH，或3-COOH，或2-COOCH，或3-COOCH，或2-COOCH，利尿，消炎和镇痛作用。

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公开/公告号UA94866C2

专利类型
公开/公告日2011-06-10

原文格式PDF
申请/专利权人 NATIONAL PHARMACEUTICAL UNIVERSITY;
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申请/专利号UAA201007853
发明设计人 CHERNYKH VALENTYN PETROVYCH;HEORHIANTS VIKTORIA AKOPIVNA;BANNYI IVAN PROKOPOVYCH;BANNA NATALIA IVANIVNA;SAVCHENKO VIKTOR MYKOLAIOVYCH;KOLESNIKOV OLEKSII VOLODYMYROVYCH;HLUSCHENKO ALLA VOLODYMYRIVNA;
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申请日2010-06-23
分类号C07C233/02;A61K31/197;A61P7/10;A61P25/08;A61P29;
国家 UA
入库时间 2022-08-21 18:04:22

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