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ANTIBODIES AGAINST INSULIN-LIKE GROWTH FACTOR I RECEPTOR COMPRISING A SUGAR CHAIN AT ASPARAGINE 297 WITH BETWEEN 20 TO 50 FUCOSE
ANTIBODIES AGAINST INSULIN-LIKE GROWTH FACTOR I RECEPTOR COMPRISING A SUGAR CHAIN AT ASPARAGINE 297 WITH BETWEEN 20 TO 50 FUCOSE
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机译:我所接受的抗胰岛素样生长因子的抗体包括糖精在297型糖精中的糖链含量在20%至50%之间
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摘要
Disclosed is an antibody binding to IGF-IR and being glycosylated with a sugar chain at amino acid asparagine located at position 297 in the Fc region, said antibody being characterized in that the amount of fucose within said sugar chain is between 20% and 50%. Further disclosed are pharmaceutical composition comprising said antibody and uses there in the manufacture of a medicament for the treatment of cancer.
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