首页> 外国专利> RE-ESTABLISHMENT OF BLOOD FLOW IN BLOCKED HUMAN ARTERIES BY TRANSFERRING NANO-ENCAPSULATED DRUG THROUGT MEDICAL DEVICES, DESIGNED FOR THE SAME AND RELEASING THE NANO-ENCAPSULATED DRUG IN HUMAN ARTERY WITH BODY PH.

RE-ESTABLISHMENT OF BLOOD FLOW IN BLOCKED HUMAN ARTERIES BY TRANSFERRING NANO-ENCAPSULATED DRUG THROUGT MEDICAL DEVICES, DESIGNED FOR THE SAME AND RELEASING THE NANO-ENCAPSULATED DRUG IN HUMAN ARTERY WITH BODY PH.

机译：通过将纳米囊化的药物转移到医疗设备中来重新设计阻塞的人体动脉中的血流量，这些装置是为相同的目的设计的，并释放人体pH值下的人体囊化的药物。

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The invention describes a Drug Releasing Medical Device (DRMD) with nano-encapsulated drug particles of different sizes coated around an abluminal surface of DRMD, which provides for a size-dependent penetration of drug into one or more layers of a body vessel. Nano-particies of drug are encapsulated with one or more of, naturally occurring phospholipids, excipients obtained from blood and lipoids, for enhanced drug release, bioavailability and biocompatibility. DRDM further includes a stent and a balloon. One or more portions of the balloon and the stent are coated with the nano-encapsulated drug particles such that, the nano-encapsulated drug particles coated on the balloon provide for immediate drug release, and the nano-encapsulated drug particles coated on the stent provides for sustained release of the drug

机译：本发明描述了一种药物释放医疗器械（DRMD），其具有围绕DRMD的管腔表面涂覆的不同尺寸的纳米封装的药物颗粒，其提供了尺寸依赖性的药物渗透进入人体血管的一层或多层。药物的纳米颗粒被一种或多种天然存在的磷脂，从血液和脂质中获得的赋形剂包裹起来，以增强药物的释放，生物利用度和生物相容性。 DRDM还包括支架和球囊。球囊和支架的一个或多个部分涂覆有纳米囊封的药物颗粒，从而，涂覆在球囊上的纳米囊封的药物颗粒提供了立即释放的药物，而涂覆在支架上的纳米囊封的药物颗粒提供了立即释放。持续释放药物

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公开/公告号IN2009MU01324A

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公开/公告日2010-12-03

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申请/专利号IN1324/MUM/2009
发明设计人 DOSHI MANISH;SHERDLWALA DIVYESH;GANDHI PANKAJ;SOJITRA PRAKASH;VYAS ASHWIN;MURTHY ZAGABATHUNI VENKATA PANCHAKSHARI;
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申请日2009-05-29
分类号A61K47/32;A61K47/02;A61K9/51;
国家 IN
入库时间 2022-08-21 18:05:53

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