首页> 外国专利> The method, as well as the use of at least a polymorphism for the determination and evaluation of the risk of a subject develop acute coronary su00ecdrome primers, probes and / or nucleotu00ecdicos, microarranjo of nucleic acids and antibodies, method for screening of compounds, as well as to guarantee Evaluation of sensitivity of a subject can get it for me, kit and use of an agent capable of modulating the activity of mmp12

The method, as well as the use of at least a polymorphism for the determination and evaluation of the risk of a subject develop acute coronary su00ecdrome primers, probes and / or nucleotu00ecdicos, microarranjo of nucleic acids and antibodies, method for screening of compounds, as well as to guarantee Evaluation of sensitivity of a subject can get it for me, kit and use of an agent capable of modulating the activity of mmp12

机译：该方法以及至少多态性在确定和评估受试者风险中的用途开发了急性冠状动脉综合征引物，探针和/或核苷酸，核酸和抗体的微构象，化合物的筛选以及确保对受试者敏感性的评估可以为我提供帮助，试剂盒和使用能够调节mmp12活性的试剂

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The method, as well as the use of at least a polymorphism for the determination and evaluation of the risk of a subject develop acute coronary su00ecndrome primers, probes and / or nucleotu00ecdicos, microarranjo of nucleic acids and antibodies, method for screening of compounds, as well as Ava Evaluation of sensitivity of a subject can get it for me, kit and use of an agent capable of modulating the activity of MMP1 2.The present invention relates to methods for the assessment of risk of developing acute coronary syndrome (ACS) in smokers and non-smokers, using analysis of genetic polymorphisms. The present invention also relates to the use of genetic polymorphisms in the risk assessment of a subject to develop ACS.Probes and primers nucleotu00eddicos, kits, and microarranjos suitable for this evaluation are also presented.

机译：该方法以及至少多态性在确定和评估受试者风险中的用途开发了急性冠状动脉综合征引物，探针和/或核苷酸，核酸和抗体的微构象，化合物的筛选以及Ava对受试者敏感性的评估可以为我，试剂盒和能够调节MMP1 2活性的试剂的使用获得。本发明涉及评估罹患急性冠状动脉的风险的方法使用遗传多态性分析对吸烟者和非吸烟者的哮喘综合征（ACS）。本发明还涉及遗传多态性在开发ACS的受试者的风险评估中的用途。还提供了适合于该评估的探针和引物，核苷酸，试剂盒和微arranjos。

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公开/公告号BRPI0618450A2

专利类型
公开/公告日2011-08-30

原文格式PDF
申请/专利权人 SYNERGENZ BIOSCIENCE LIMITED;
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申请/专利号BR2006PI18450
发明设计人 ROBERT PETER YOUNG;
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申请日2006-11-10
分类号C12Q1/68;C07K16;C12N15/11;
国家 BR
入库时间 2022-08-21 18:07:10

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