首页> 外国专利> compound or salts, solvates or solvated salts thereof, use thereof, pharmaceutical composition, method of treating 5ht6 mediated disorders and for the treatment of alzheimer's disease, cognitive impairment associated with schisophrenia, obesity and / or parkinson's disease, and , agent for the prevention or treatment of alzheimer's disease, cognitive impairment associated with schisophrenia, obesity and / or parkinson's disease

compound or salts, solvates or solvated salts thereof, use thereof, pharmaceutical composition, method of treating 5ht6 mediated disorders and for the treatment of alzheimer's disease, cognitive impairment associated with schisophrenia, obesity and / or parkinson's disease, and , agent for the prevention or treatment of alzheimer's disease, cognitive impairment associated with schisophrenia, obesity and / or parkinson's disease

机译：化合物或其盐，溶剂化物或溶剂化物盐，其用途，药物组合物，治疗5ht6介导的疾病和治疗阿尔茨海默氏病，与精神分裂症，肥胖症和/或帕金森氏病相关的认知障碍的方法，以及阿尔茨海默氏病，精神分裂症相关的认知障碍，肥胖症和/或帕金森氏病的治疗

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摘要

COMPOUND OR SALTS, SOLVATES OR SOLVATED SALTS OF THE SAME, USE OF THE SAME, PHARMACEUTICAL COMIPOSITION, METHOD OF TREATING DISORDERS MEDIATED BY 5HT6 AND FOR THE TREATMENT OF ALZHEIMER EVIL, DEGREASING OF EAGLE, ORGANIZED ORGANIZATION , AGENT FOR THE PREVENTION OR TREATMENT OF ALZHEIMER'S EVIL, COGNITIVE DETERIORATION ASSOCIATED WITH SCHISOPHRENIA, OBESITY AND / OR EVIL OF PARKINSON. The present invention relates to new compounds of the formula (I) in which R ^ 1 ^ to R ^ 12 ^, P, X, Q and n are as defined as in formula (I), or salts, solvates or solvated salts thereof , processes for their preparation and the new intermediates used in the preparation of these pharmaceutical formulations containing said compounds and the use of said compounds in therapy.

机译：相同的化合物或盐，溶剂化物或溶剂化物的盐，相同的化合物的使用，药物组成，治疗5HT6介导的疾病的方法以及用于处理Alzerimer恶性，变质的EAGLE，组织的有机组织，代理商的组织，代理商与精神分裂症，肥胖和/或帕金森病相关的恶性，认知力下降。本发明涉及式（I）的新化合物或其盐，溶剂化物或溶剂化物盐，其中R ^ 1 ^至R ^ 12 ^，P，X，Q和n如式（I）所定义。，其制备方法以及用于制备包含所述化合物的这些药物制剂的新中间体，以及所述化合物在治疗中的用途。

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公开/公告号BRPI0609800A2

专利类型
公开/公告日2011-10-11

原文格式PDF
申请/专利权人 ASTRAZENECA AB;
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申请/专利号BR2006PI09800
发明设计人 GUNNAR NORDVALL;CARL PETERSSON;LASZLO RAKOS;DANIEL SOHN;
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申请日2006-05-22
分类号C07C311/37;A61K31/18;A61K31/4025;A61K31/435;A61K31/495;A61P25/16;A61P25/18;A61P25/28;C07D207/12;C07D213/75;C07D215/38;C07D217/06;C07D239/69;C07D311/04;C07D405/04;
国家 BR
入库时间 2022-08-21 18:07:18

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