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Methods to identify patients at risk of developing adverse events during treatment with antidepressant medication
Methods to identify patients at risk of developing adverse events during treatment with antidepressant medication
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机译:识别使用抗抑郁药治疗期间有发生不良事件风险的患者的方法
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摘要
The invention provides a method of screening patients to identify those patients more likely to exhibit an increased risk of treatment-emergent suicidal ideation comprising: (a) obtaining a sample of genetic material from the patients, and (b) assaying the sample for the presence of a genotype in the patients which is associated with an increased risk of treatment-emergent suicidal ideation, wherein the genotype is characterized by a polymorphism in a gene selected from the group consisting of glutamine receptor, ionotropic, kainate 2 (GRIK2); glutamate receptor ionotropic AMPA 3 (GRIA3); and combinations thereof.
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