首页> 外国专利> 1-(1H-1,2,4-Triazol-1-YL)Butan-2-OL Derivative For Pharmaceutical Use, and The Use Of a 1-(1H-1,2,4-Triazol-1-YL)Butan-2-OL Derivative With Substantially Undefined Crystal Shape For Preparing Said 1-(1H-1,2,4-Triazol-1-YL)Butan-2-OL Derivative

1-(1H-1,2,4-Triazol-1-YL)Butan-2-OL Derivative For Pharmaceutical Use, and The Use Of a 1-(1H-1,2,4-Triazol-1-YL)Butan-2-OL Derivative With Substantially Undefined Crystal Shape For Preparing Said 1-(1H-1,2,4-Triazol-1-YL)Butan-2-OL Derivative

机译：用于药物用途的1-（1H-1,2,4-三唑-1-基）丁-2-OL衍生物和1-（1H-1,2,4-三唑-1-基）丁的用途用于制备所述1-（1H-1,2,4-三唑-1-基）丁-2-OL衍生物的晶体形状基本不确定的-2--2-OL衍生物

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摘要

The present invention relates to voriconazole, processes of preparing voriconazole, and pharmaceutical compositions and therapeutic uses thereof. In particular, the present invention also relates to voriconazole prepared from voriconazole having a substantially undefined shape and/or crystal habit. The invention further relates to voriconazole having a modified sphericity factor and/or specific surface area and/or Sauter diameter compared to voriconazole known from the prior art.

机译：本发明涉及伏立康唑，伏立康唑的制备方法，药物组合物及其治疗用途。特别地，本发明还涉及由具有基本未定义的形状和/或晶体习性的伏立康唑制备的伏立康唑。本发明还涉及与现有技术已知的伏立康唑相比具有改进的球形度因子和/或比表面积和/或Sauter直径的伏立康唑。

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公开/公告号US2011159096A1

专利类型
公开/公告日2011-06-30

原文格式PDF
申请/专利权人 ERNESTO DURAN LOPEZ;JUAN CONTRERAS LASCORZ;
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申请/专利号US20100842540
发明设计人 ERNESTO DURAN LOPEZ;JUAN CONTRERAS LASCORZ;
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申请日2010-07-23
分类号A61K31/506;A61K9;A61K9/14;A61K9/28;A61P31/10;B32B5;B02C19/06;B02C23/08;
国家 US
入库时间 2022-08-21 18:12:29

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