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Brain tumor stem cell markers in primary neuronal tumors and gliomas of the brain and CD24 as a diagnostic and therapeutic target
Brain tumor stem cell markers in primary neuronal tumors and gliomas of the brain and CD24 as a diagnostic and therapeutic target
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机译：原发性脑神经瘤和脑胶质瘤中的脑肿瘤干细胞标志物和CD24作为诊断和治疗靶标
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摘要
The present invention is directed to methods of treating a primary brain tumor and preventing the migratory spread of a primary brain tumor in a subject. These methods involve utilizing the CD24 surface protein selectively expressed on tumor progenitor cells as a therapeutic target as well as a means for directing oncolytic therapeutics directly to the tumor site. The present invention further relates to methods of diagnosing the presence of a brain tumor and monitoring the status of the brain tumor in a subject based on CD24 expression in tumor progenitor cells.
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