首页> 外国专利> BRCA1 mRNA expression levels predict survival in breast cancer patients treated with neoadjuvant chemotherapy

BRCA1 mRNA expression levels predict survival in breast cancer patients treated with neoadjuvant chemotherapy

机译:BRCA1 mRNA表达水平预测新辅助化疗治疗的乳腺癌患者的生存

摘要

The invention relates to methods for predicting the clinical outcome of a patient which suffers from breast cancer based on the expression levels of BRCA1, wherein low BRCA1 expression levels are indicative of a good prognosis. Moreover, the invention relates to methods for predicting the response to a neoadjuvant therapy based on a combination of an anti-metabolite, an intercalating agent and an alkylating agent of a patient which suffers from breast cancer based on the expression levels of BRCA1.
机译:本发明涉及基于BRCA1的表达水平预测患有乳腺癌的患者的临床结果的方法,其中低的BRCA1表达水平指示良好的预后。此外,本发明涉及基于BRCA1的表达水平,基于患有乳腺癌的患者的抗代谢物,嵌入剂和烷基化剂的组合来预测对新辅助疗法的反应的方法。

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