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Prophylactic agent to use a protective effect in neuronal cells of the rare sugar, therapeutic drugs, food for specified health use

机译:在稀有糖,治疗药物,特定健康食品中对神经细胞具有保护作用的预防剂

摘要

PROBLEM TO BE SOLVED: To provide a cell death inhibitor consisting of rare sugar(s), and to provide a prophylactic drug, a therapeutic drug and a specific health food for diseases including a neurodegenerative disease like prion disease caused by cell death with the inhibitor as active ingredient.;SOLUTION: The neurocyte death inhibitor utilizing the protective activity of rare sugar(s), preferably D-psicose and/or D-allose, in neurocyte is provided. The prophylactic and/or therapeutic drug contains the inhibitor as active ingredient and is to be used for preventing and/or treating neurodegenerative diseases, neonatal nuclear jaundice, muscular dystrophy, cerebral ischemia or tardive neurocyte death thereafter, prion disease, and the advance of the symptoms of the dysfunction of cerebral nerve tissue or the same under transplantation, wherein the neurodegenerative diseases include Alzheimer's disease, spinal muscular atrophy, amyotrophic lateral sclerosis, Parkinson's disease, Huntington disease, retinitis pigmentosa, glaucoma and cerebellar degeneration. A preservative for cerebral nerve tissue and/or cerebral neurocyte with this inhibitor as active ingredient and a medium for culturing cerebral nerve tissue cell containing this inhibitor are also provided, respectively.;COPYRIGHT: (C)2005,JPO&NCIPI
机译:解决的问题:提供由稀有糖组成的细胞死亡抑制剂,并提供预防药物,治疗药物和特定保健食品,用于治疗由该抑制剂引起的细胞死亡引起的神经退行性疾病如like病毒疾病解决方案:提供了一种神经细胞死亡抑制剂,该细胞利用了稀有糖(优选D-庚糖和/或D-阿洛糖)在神经细胞中的保护活性。预防和/或治疗药物含有抑制剂作为活性成分,并用于预防和/或治疗神经退行性疾病,新生儿核黄疸,肌肉营养不良,其后脑缺血或迟发性神经细胞死亡,disease病毒病及其进展。移植后脑神经组织功能障碍的症状,其中神经退行性疾病包括阿尔茨海默氏病,脊髓性肌萎缩,肌萎缩性侧索硬化症,帕金森氏病,亨廷顿病,色素性视网膜炎,青光眼和小脑变性。还分别提供了以该抑制剂为有效成分的脑神经组织和/或脑神经细胞的防腐剂,以及含有该抑制剂的培养脑神经组织细胞的培养基。版权所有:(C)2005,JPO&NCIPI

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