首页> 外国专利> ANTIBODY FOR SPECIFICALLY RECOGNIZING AGLYCON HAVING ACETYLCHOLINE RECEPTOR CLUSTER FORMATION-INHIBITING ACTIVITY, ACETYLCHOLINE RECEPTOR CLUSTER FORMATION ABILITY-PROMOTING AGENT CONTAINING THE ANTIBODY, AND AGLYCON-REMOVING COLUMN FILLED WITH THE ANTIBODY HAVING ACETYLCHOLINE RECEPTOR CLUSTER FORMATION ABILITY-INHIBITING ACTIVITY

ANTIBODY FOR SPECIFICALLY RECOGNIZING AGLYCON HAVING ACETYLCHOLINE RECEPTOR CLUSTER FORMATION-INHIBITING ACTIVITY, ACETYLCHOLINE RECEPTOR CLUSTER FORMATION ABILITY-PROMOTING AGENT CONTAINING THE ANTIBODY, AND AGLYCON-REMOVING COLUMN FILLED WITH THE ANTIBODY HAVING ACETYLCHOLINE RECEPTOR CLUSTER FORMATION ABILITY-INHIBITING ACTIVITY

机译：专门识别具有乙酰胆碱受体团簇形成抑制活性的糖的抗体，包含抗体的乙酰胆碱受体团簇形成能力的促进糖的乙酰胆碱受体团聚活性的消除剂和消除带有糖键的凝胶化的胶结的抗体。

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PPROBLEM TO BE SOLVED: To develop agents for treating diseases caused by the damage of acetylcholine receptor cluster formation ability. PSOLUTION: It has been newly found that the splicing variant of aglycon having a function for inhibiting acetylcholine receptor cluster formation ability exists. On the basis of the knowledge, it has been found that an antibody for specifically recognizing the aglycon having an acetylcholine receptor cluster formation-inhibiting activity can be used for the acetylcholine receptor cluster formation ability-promoting agent and an aglycon-removing column having acetylcholine receptor cluster formation-inhibiting activity. PCOPYRIGHT: (C)2011,JPO&INPIT

机译：

要解决的问题：开发用于治疗由乙酰胆碱受体簇形成能力受损引起的疾病的药物。

解决方案：最近发现，存在具有抑制乙酰胆碱受体簇形成能力的功能的糖苷配基的剪接变体。基于该知识，发现可以将用于特异性识别具有乙酰胆碱受体簇形成抑制活性的糖苷配基的抗体用于乙酰胆碱受体簇形成能力促进剂和具有乙酰胆碱受体的糖苷去除柱。团簇形成抑制活性。

版权：（C）2011，日本特许厅＆INPIT 展开▼

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公开/公告号JP2011173793A

专利类型
公开/公告日2011-09-08

原文格式PDF
申请/专利权人 KANAZAWA UNIV;
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申请/专利号JP20100036739
发明设计人 YOSHIKAWA HIROAKI;YOKOYAMA SHIGERU;MARUTA TAKAHIRO;
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申请日2010-02-23
分类号C07K16/18;C12N15/09;C07K7/06;C07K14/47;C12Q1/02;A61K39/395;A61P21/04;A61P21/02;A61P21;A61P25/28;A61P25/16;A61M1/36;G01N30/88;G01N33/15;G01N33/50;C12P21/08;
国家 JP
入库时间 2022-08-21 18:23:24

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