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bildverarbeitungsbasierte calculation of scores for the expression of estrogen and progesterone receptors

机译:bildverarbeitungsbasierte计算雌激素和孕激素受体表达的分数

摘要

A method of scoring Oestrogen and Progesterone Receptors expression (ER and PR) from histological images determines the percentage of brown image blob area in total blob area and derives percentage thresholds to quantify scoring. Brown blob area proportion is then compared with the thresholds to provide a first contribution to scoring of ER or PR. The number of relatively dark pixels is then counted, pixel number thresholds are determined to quantify scoring, and the number of relatively dark pixels is compared with the thresholds to provide a second contribution scoring of ER or PR. The two contributions are then added to provide an overall scoring in the range 0 to 8 which may be taken as a final score or it may be scaled to a conventional range 0 to 3.
机译:一种从组织学图像中对雌激素和孕激素受体表达(ER和PR)进行评分的方法,可确定棕色图像斑点面积在总斑点面积中所占的百分比,并得出百分比阈值以量化得分。然后将布朗斑点面积比例与阈值进行比较,以为ER或PR评分提供第一贡献。然后计数相对暗像素的数量,确定像素数量阈值以量化得分,并且将相对暗像素的数量与阈值进行比较,以提供ER或PR的第二贡献得分。然后将这两个贡献相加,以提供0到8范围内的总体得分,该得分可以作为最终得分,也可以缩放到常规范围0到3。

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