首页> 外国专利> Determining an effective or ineffective chemotherapeutic drugs for patients by individual in vitro testing of live tumor cells before or during therapy, where the drugs are further tested in presence of e.g. oxygen deficiency and glucose

Determining an effective or ineffective chemotherapeutic drugs for patients by individual in vitro testing of live tumor cells before or during therapy, where the drugs are further tested in presence of e.g. oxygen deficiency and glucose

机译:通过在治疗之前或治疗过程中对活体肿瘤细胞进行单独的体外测试,确定对患者有效或无效的化疗药物,其中在存在下列药物的情况下进一步测试药物:缺氧和葡萄糖

摘要

Determination of effective or ineffective chemotherapeutic drugs (single or in combination) for patients by individual in vitro testing of live tumor cells, before or during the therapy, where the effective or ineffective chemotherapeutic drugs are further tested in the presence of oxygen deficiency (hypoxia), glucose, transketolase-like 1 (TKTL1) inhibitors, an inhibitor for certain parts of the energy metabolism, and a medicament against cancer cells, is claimed.
机译:在治疗前或治疗中,通过在活体肿瘤细胞中进行单独的体外测试,确定对患者有效或无效的化疗药物(单一或组合),其中在缺氧(缺氧)的情况下进一步测试有效或无效的化疗药物本发明要求保护葡萄糖,葡萄糖,转酮醇酶样1(TKTL1)抑制剂,能量代谢某些部分的抑制剂和抗癌细胞的药物。

著录项

  • 公开/公告号DE102008058984A1

    专利类型

  • 公开/公告日2010-06-17

    原文格式PDF

  • 申请/专利权人 KISCHKEL FRANK;

    申请/专利号DE20081058984

  • 发明设计人

    申请日2008-11-25

  • 分类号C12Q1/02;

  • 国家 DE

  • 入库时间 2022-08-21 18:28:38

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