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METHOD FOR DETERMINING indications for antioxidant therapy in patients in the perioperative period

机译:确定围手术期患者抗氧化治疗适应症的方法

摘要

A method of determining indications for antioxidant therapy in patients in the perioperative period, including laboratory testing of blood serum, characterized in that determined by kinetic curve induced luminol chemiluminescence: maximum intensity Imax mV light sum reactions S mV · s, antioxidant activity coefficient K = Imax / s cu, at the value Imax is greater than 25 mV, s greater than 10,000 mV · s, the coefficient K is less than 0.0025 cu diagnosing oxidative stress with decompensation of the antioxidant defense system and carry out correction of antioxidant defense as follows: in step induction of general anesthesia drug intravenously administered meksidol 250 mg, dissolved in 200 ml of 0.9% saline and dalargin - in step core anesthetic maintenance intravenously at a dose of 1.0 ± 0.55 mg / kg, in pace 3.0 ± 0.15 mg / kg per hour.
机译:一种确定围手术期患者抗氧化剂治疗适应症的方法,包括对血清进行实验室检查,其特征在于,通过动力学曲线诱导的鲁米诺化学发光确定:最大强度Imax mV轻和反应S mV·s,抗氧化剂活性系数K = Imax / s cu,Imax大于25 mV,s大于10,000 mV·s,系数K小于0.0025 cu,通过抗氧化防御系统的失代偿诊断氧化应激并按如下方式进行抗氧化防御的校正:在全麻药物的分步诱导中静脉内注射250 mg的美他多尔,溶于200 ml的0.9%盐水和达拉根中-在分步麻醉中以1.0±0.55 mg / kg的剂量静脉内维持麻醉,步伐为3.0±0.15 mg / kg每小时。

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