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Self-assembled polymeric nanoparticles containing coenzyme Q10 and skin-care compositions for exteral application, containing the nanoparticles
Self-assembled polymeric nanoparticles containing coenzyme Q10 and skin-care compositions for exteral application, containing the nanoparticles
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机译：含有辅酶Q10的自组装聚合物纳米颗粒和用于外用的皮肤护理组合物，其中包含纳米颗粒
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摘要
The present invention provides a self-associative polymer nanoparticle and an external skin composition containing the same, in which an insoluble substance coenzyme Q10 is collected and solubilized in an aqueous solution using an amphiphilic polymer having polycaprolactone as a hydrophobic block and polyethylene glycol as a hydrophilic block. It is about. The nanoparticles according to the present invention utilize the self-associability of the amphiphilic polymer, and are easily obtained without undergoing a mechanical process or a special process requiring high energy, and an aqueous solution of the insoluble material coenzyme Q10 using the amphiphilic polymer. Since it is prepared to be uniformly dispersed in the phase, it is applicable to various external formulations including cosmetics, and when applied to the skin, the skin absorption rate may be improved due to the nanonized size.;Coenzyme Q10 * Amphiphilic polymer * Nanoparticles * Self-assembly * Cosmetic composition * Block copolymer
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