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METHOD FOR DIFFERENTIATING HUMAN EMBRYONIC STEM CELL TO CARDIAC PROGENITOR CELLS OR CARDIAC MYOCYTE USING TREATMENT OF GAMMA SECRETASE INHIBITOR AND VOLUMINAL CONTROL OF CULTURE SOLUTION
METHOD FOR DIFFERENTIATING HUMAN EMBRYONIC STEM CELL TO CARDIAC PROGENITOR CELLS OR CARDIAC MYOCYTE USING TREATMENT OF GAMMA SECRETASE INHIBITOR AND VOLUMINAL CONTROL OF CULTURE SOLUTION
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机译:通过γ分泌酶抑制剂的处理和培养液的体积控制将人胚胎干细胞分化为心脏祖细胞或心肌细胞的方法
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摘要
The present invention relates to a method for promoting differentiation of human embryonic stem cells into myocardial precursors or cardiomyocytes using a gamma secretase inhibitor treatment and volume control of the culture medium, and more specifically, an agent for culturing human embryonic stem cells in an undifferentiated state. Stage 1; And a second step of treating the undifferentiated human embryonic stem cells with a gamma secretase inhibitor and differentiating them in a reduced volume of culture medium, unlike conventional differentiation methods, without having to go through the embryonic body formation step. The present invention relates to a method for promoting differentiation of human embryonic stem cells into myocardial precursors or cardiomyocytes, which can significantly shorten the differentiation period of the furnace and improve its differentiation efficiency.;Human Embryonic Stem Cells, Gamma Secretase Inhibitors, Myocardium, Differentiation
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