首页> 外国专利> BIOMARKER FOR DETECTING ENVIRONMENTALLY HAZARDOUS CHEMICALS AND METHOD FOR DETECTING HAZARDOUS CHEMICALS USING THE SAME

BIOMARKER FOR DETECTING ENVIRONMENTALLY HAZARDOUS CHEMICALS AND METHOD FOR DETECTING HAZARDOUS CHEMICALS USING THE SAME

机译:用于检测环境危险化学品的生物标记和使用相同方法检测危险化学品的方法

摘要

PURPOSE: A biomarker for detecting environmental harzadous substance is provided to use in evaluation of virtual danger depending statistics and toxicity problem of long-term exposure. CONSTITUTION: A method for screening biomarker gene for detecting volatile organic compound(VOC), persistant organic pollutant(POP) or polycyclic aromatic hydrocarbon(PAH) comprises: a first step of separately treating to animal cells or tissue sample except for human to detect gene expression profile; a second step of detecting gene expression profile of a control sample in the same condition as the first step; and a third step of selecting gene which has significant change between test sample and control sample in expression profile to determine biomarker gene for detecting VOC, POP, or PAH.
机译:目的:提供一种用于检测环境有害物质的生物标记物,用于根据长期暴露的统计数据和毒性问题评估虚拟危险。组成:一种用于检测生物标志物基因的方法,以检测挥发性有机化合物(VOC),持久性有机污染物(POP)或多环芳烃(PAH),包括:第一步,除人类检测基因外,分别处理动物细胞或组织样品表达谱;第二步,在与第一步相同的条件下检测对照样品的基因表达谱;第三步,选择在表达谱中测试样品和对照样品之间有显着变化的基因,以确定用于检测VOC,POP或PAH的生物标记基因。

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