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首页> 外国专利> PHARMACEUTICAL COMPOSITION FOR TREATMENT AND PREVENTION OF DIABETES OR OBESITY COMPRISING DPP-IV INHIBITOR AND OTHER ANTIDIABETIC DRUG OR ANTIOBESITIC DRUG

PHARMACEUTICAL COMPOSITION FOR TREATMENT AND PREVENTION OF DIABETES OR OBESITY COMPRISING DPP-IV INHIBITOR AND OTHER ANTIDIABETIC DRUG OR ANTIOBESITIC DRUG

机译：包含DPP-IV抑制剂和其他抗糖尿病药物或抗糖尿病药物的用于预防和治疗糖尿病或肥胖的药物组合物

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PURPOSE: A composition containing DPP-IV(Dipeptidyl Peptidase-IV) inhibition compound and other anti-diabetes or anti-obesity is provided to effectively suppress blood glucose. CONSTITUTION: A pharmaceutical composition for preventing and treating diabetes or obesity contains a compound of chemical formula 1, pharmaceutically acceptable salt, hydrate, or solvate thereof, and other anti-diabetes or anti-obesity drug as active ingredient. The compound of chemical formula 1 is DDP-IV(Dipeptidyl Peptidase-IV) inhibitor. The other anti-diabetes or anti-obesity drug is biguanide drug, insulin sensitizer, insulin secretagogue, alpha-glucosidase inhibitor, or cannabinoid receptor 1 antagonist. The biguanide drug is metformin, buformin, or phenformin. A pharmaceutical composition contains the compound of chemical formula 1, or pharmaceutically acceptable salt thereof and biaguanide drug in a ratio of 9:1~1:3 based on ED30 value.
机译：目的：提供一种包含DPP-IV（二肽基肽酶-IV）抑制化合物和其他抗糖尿病或抗肥胖症的组合物，以有效抑制血糖。组成：用于预防和治疗糖尿病或肥胖症的药物组合物，包含化学式1的化合物，其药学上可接受的盐，水合物或溶剂化物，以及其他抗糖尿病或抗肥胖药作为有效成分。化学式1的化合物是DDP-IV（二肽基肽酶-IV）抑制剂。其他抗糖尿病或抗肥胖药是双胍类药物，胰岛素增敏剂，胰岛素促分泌剂，α-葡萄糖苷酶抑制剂或大麻素受体1拮抗剂。双胍类药物为二甲双胍，丁苯双胍或苯乙双胍。药物组合物包含化学式1的化合物或其药学上可接受的盐和双胍类药物，其基于ED 30值的比例为9∶1至1∶3。

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