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METHOD, SYSTEM AND SOFTWARE ARRANGEMENT FOR COMPARATIVE ANALYSIS AND PHYLOGENY WITH WHOLE-GENOME OPTICAL MAPS

机译:全基因组光学图谱的比较分析和系统发育的方法,系统和软件安排

摘要

The present invention provides a method for organizing genomic information from multiple organisms. In one embodiment of the invention, phylogenetic trees can be constructed for the organisms. The method of the present invention is termed CAPO, Comparative Analysis and Phylogeny with Optical-Maps. Optical maps of organisms are obtained and phylogeny between the organisms is determined by optical map comparison and bipartite graph matching between the organisms, as, for example, computed by a stable marriage algorithm.
机译:本发明提供了一种用于组织来自多种生物的基因组信息的方法。在本发明的一个实施方案中,可以为生物构建系统发育树。本发明的方法被称为CAPO,比较分析和利用光学图谱的系统发育。获得生物的光学图,并通过光学图比较和生物之间的二分图匹配来确定生物之间的系统发育,例如通过稳定的婚姻算法来计算。

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