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SYSTEM AND METHOD FOR ANALYTE MEASUREMENT USING A NONLINEAR SAMPLE RESPONSE

机译:使用非线性样本响应进行分析物测量的系统和方法

摘要

The systems and methods of the present invention utilize a linear component of a non-linear, Faradaic current response generated by a biological fluid sample when an AC excitation potential sufficient to produce such a Faradaic current response is applied to the sample, in order to calculate the concentration of a medically significant component in the biological fluid sample. The current response is created by the excitation of electrochemical processes within the sample by the applied potential. Typically, the linear component of the current response to an applied AC potential contains phase angle and/or admittance information that may be correlated to the concentration of the medically significant component. Also typically, the fundamental linear component of the current response is utilized in the disclosed systems and methods. Harmonics of the fundamental linear component may also be used. Other methods and devices are disclosed.
机译:当足以产生这样的法拉第电流响应的AC激励电势施加到样品时,本发明的系统和方法利用由生物流体样品产生的非线性法拉第电流响应的线性分量,以便计算生物流体样品中医学上重要成分的浓度。电流响应是通过施加的电势激发样品内的电化学过程而产生的。典型地,电流对施加的AC电势的响应的线性分量包含相角和/或导纳信息,其可以与医学上重要的分量的浓度相关。同样典型地,在所公开的系统和方法中利用电流响应的基本线性分量。也可以使用基本线性分量的谐波。公开了其他方法和设备。

著录项

  • 公开/公告号EP2147306A1

    专利类型

  • 公开/公告日2010-01-27

    原文格式PDF

  • 申请/专利权人 ROCHE DIAGNOSTICS GMBH;F. HOFFMANN-LA ROCHE AG;

    申请/专利号EP20080758428

  • 发明设计人 BUCK HARVEY B.;

    申请日2008-05-09

  • 分类号G01N33/487;C12Q1/00;G01N27/02;G01N27/49;

  • 国家 EP

  • 入库时间 2022-08-21 18:36:14

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