首页> 外国专利> PROCESS FOR LABELING A RIBONUCLEIC ACID, AND LABELED RNA FRAGMENTS WHICH ARE OBTAINED THEREBY

PROCESS FOR LABELING A RIBONUCLEIC ACID, AND LABELED RNA FRAGMENTS WHICH ARE OBTAINED THEREBY

机译:由此获得核糖核酸的标签和标记的RNA片段的方法

摘要

The present invention relates to a process for labeling with signalamplification a ribonucleic acid (RNA),characterized in that it comprises: fragmenting the RNA, fixing a first ligandto the terminal phosphate which is located at the 3' end and/orthe 5' end of each fragment of said RNA, said terminal phosphate having beenreleased during the fragmentation, and binding alabeling agent to said first ligand. The invention is preferably applied inthe field of medical diagnosis.
机译:用信号标记的方法技术领域本发明涉及一种用信号标记的方法。扩增核糖核酸(RNA),其特征在于包括:片段化RNA,固定第一配体到位于3'端和/或所述RNA的每个片段的5'末端,所述末端磷酸酯已经被在碎片过程中释放,并结合所述第一配体的标记剂。本发明优选地应用于医学诊断领域。

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