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COMPARATIVE FLUORESCENCE HYBRIDIZATION TO OLIGONUCLEOTIDE MICROARRAYS
COMPARATIVE FLUORESCENCE HYBRIDIZATION TO OLIGONUCLEOTIDE MICROARRAYS
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机译:荧光杂交对寡核苷酸微阵列的杂交
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摘要
The present invention provides methods of determining relative copy number oftarget nucleic acid sequences and precise mappingof chromosomal abnormalities associated with disease. The methods of theinvention use target nucleic acid sequences immobilized on asolid surface, to which a sample comprising two sets of differentially labelednucleic acid sequences are hybridized. The hybridization ofthe labeled nucleic acid sequences to the solid surface is then detected usingstandard techniques.
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