首页> 外国专利> compound or a pharmaceutically acceptable salt thereof, process for preparing a compound or a pharmaceutically acceptable salt thereof, pharmaceutical composition, use of a compound or a pharmaceutically acceptable salt thereof, and methods for producing a drug inhibiting effect. b-raf in a warm-blooded animal, for producing an anti-cancer effect on a warm-blooded animal and for treating diseases of an animal in a warm-blooded animal

compound or a pharmaceutically acceptable salt thereof, process for preparing a compound or a pharmaceutically acceptable salt thereof, pharmaceutical composition, use of a compound or a pharmaceutically acceptable salt thereof, and methods for producing a drug inhibiting effect. b-raf in a warm-blooded animal, for producing an anti-cancer effect on a warm-blooded animal and for treating diseases of an animal in a warm-blooded animal

机译:化合物或其药学上可接受的盐,制备化合物或其药学上可接受的盐的方法,药物组合物,化合物或其药学上可接受的盐的用途以及产生药物抑制作用的方法。 b-raf在温血动物中,用于对温血动物产生抗癌作用并治疗温血动物中的动物疾病

摘要

COMPOSITE OR PHARMACEUTICALLY ACCEPTABLE SALT THEREOF, PROCESS TO PREPARE PHARMACEUTICALLY ACCEPTABLE SALT OR PHARMACEUTICALLY COMPOSITION, USE OF A COMPOUND OR PHARMACEUTICALLY ACCEPTED SALT OF THESE AND METHOD B-RAF IN A HOT BLOOD ANIMAL, FOR THE PRODUCTION OF ANTI-CANCER EFFECT ON A HOT BLOOD ANIMAL AND FOR TREATMENT OF DISEASES IN A HOT BLOOD ANIMAL. The invention relates to chemical compounds, or pharmaceutically acceptable salts thereof, of formula (1): which have B-Raf inhibitory activity, useful because of their anti-cancer activity and, therefore, in methods of treatment of B-Raf. human or animal body. The invention also relates to the manufacture of said chemicals, pharmaceutical compositions containing them and compounds for use in the manufacture of medicaments for use in producing an anti-cancer effect in a warm-blooded animal such as man.
机译:合成或可药用盐,用于制备可药用盐或可药用成分的方法,在热血生产中使用这些化合物或可药用盐在热血中用于生产热细菌动物和热血动物疾病的治疗。本发明涉及式(1)的化合物或其药学上可接受的盐:具有B-Raf抑制活性,由于其抗癌活性而有用,因此在B-Raf的治疗方法中有用。人体或动物的身体。本发明还涉及所述化学制品的制造,包含它们的药物组合物以及用于制造在温血动物例如人中产生抗癌作用的药物的化合物。

著录项

  • 公开/公告号BRPI0606930A2

    专利类型

  • 公开/公告日2009-12-01

    原文格式PDF

  • 申请/专利权人 ASTRAZENECA AB;

    申请/专利号BR2006PI06930

  • 发明设计人 BRIAN AQUILA;PAUL LYNE;TIMOTHY PONTZ;

    申请日2006-01-24

  • 分类号C07D401/04;A61K31/506;A61P31;A61P35;C07D239/42;C07D401/12;C07D403/12;

  • 国家 BR

  • 入库时间 2022-08-21 18:47:21

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