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Method of preventing differentiation of a chicken differentiable cell using chicken leukemia inhibitory factor (LIF)

机译:使用鸡白血病抑制因子(LIF)防止鸡分化细胞分化的方法

摘要

The present invention is to provide a chicken LIF gene. Based on this genetic information, LIF protein derived from the chicken can be stably supplied and it solves the problems of the creation of transgenic chickens in the past. In addition, the present invention provides not only transgenic chickens for testing purposes but also supplies the first practical transgenic stock animals. The present invention relates to leukemia inhibitory factor (LIF) shown in sequence No. 2, and the gene that encodes thereof shown in sequence No. 1, and a manufacturing method of chicken LIF. In addition, the present invention pertains to a differential preventer of the chicken differentiable cell, and a method of chicken differential prevention and a culturing method for the chicken differentiable cell using thereof, and a medium comprising thereof.
机译:本发明提供了一种鸡LIF基因。基于该遗传信息,可以稳定地供应源自鸡的LIF蛋白,并且解决了过去产生转基因鸡的问题。另外,本发明不仅提供用于测试目的的转基因鸡,而且还提供第一批实用的转基因家畜。本发明涉及序列2所示的白血病抑制因子(LIF),序列1所示的编码其的基因以及鸡LIF的制造方法。另外,本发明涉及鸡可分化细胞的差异预防剂,鸡可分化细胞的预防方法和鸡可分化细胞的培养方法以及包含其的培养基。

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