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Microfluidic System Comprising Mechanically-Actuated Microfluidic Pinch Valve

机译:包含机械驱动微流体夹管阀的微流体系统

摘要

A microfluidic system. The system comprises: (A) a microfluidics platform comprising: a compliant body having a microfluidic channel defined therein; a valve sleeve defined by a section of the microfluidic channel, the valve sleeve having a membrane wall defining part of an outer surface of the body; and a compression member for pinching the membrane wall against an opposed wall of the valve sleeve; and (B) a MEMS integrated circuit bonded to the outer surface of the body, the MEMS integrated circuit comprising: a moveable finger engaged with the compression member, the finger being configured to urge the compression member between a closed position in which the membrane wall is sealingly pinched against the opposed wall, and an open position in which the membrane wall is disengaged from the opposed wall; a thermal bend actuator associated with the finger, the actuator configured for controlling movement of the finger; and control circuitry for controlling actuation of the actuator so as to control opening and closing of the valve sleeve.
机译:微流体系统。该系统包括:(A)微流体平台,其包括:具有在其中限定的微流体通道的顺应性主体;和由微流体通道的一部分限定的阀套,该阀套具有限定了主体的外表面的一部分的膜壁。压缩构件,其将膜壁夹在阀套的相对壁上。 (B)结合到所述主体的外表面的MEMS集成电路,所述MEMS集成电路包括:与所述压缩构件接合的可动指状物,所述指状物被构造成在所述膜壁的闭合位置之间推动所述压缩构件。密封地压靠在相对壁上,并且在打开位置中膜壁与相对壁脱离。与手指相关联的热弯曲致动器,该致动器构造成用于控制手指的运动;控制电路,用于控制致动器的致动,以控制阀套的打开和关闭。

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