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TREATMENT OF HIV AND AIDS USING PROBIOTIC LACTOBACILLUS REUTERI

机译：益生性乳酸乳球菌治疗艾滋病毒和艾滋病

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摘要

A method for treating or preventing a Human Immunodeficiency Virus (HIV) infection, or treating or preventing Acquired Human Immunodeficiency Syndrome (AIDS), in a subject in need thereof, is disclosed. The method involves colonizing a genetically modified probiotic Lactobacillus reuteri RC-14 in the gastrointestinal tract of a subject, wherein the probiotic is able to secrete two or more fusion inhibitors that decrease or prevent HIV production and CD4+T cell depletion in the gastrointestinal tract.

机译：公开了一种在有需要的受试者中治疗或预防人免疫缺陷病毒（HIV）感染或治疗或预防后天性人免疫缺陷综合症（AIDS）的方法。该方法包括在受试者的胃肠道中定居转基因的益生菌罗伊氏乳杆菌 RC-14，其中所述益生菌能够分泌两种或多种减少或预防HIV产生和CD4 + T的融合抑制剂。胃肠道中的细胞消耗。 展开▼

著录项

公开/公告号US2010143305A1

专利类型

公开/公告日2010-06-10

原文格式PDF

申请/专利权人 JAMES ALLEN LEMKE;
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申请/专利号US20090633642

发明设计人 JAMES ALLEN LEMKE;
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申请日2009-12-08

分类号A61K35/74;A61P31/18;

国家 US

入库时间 2022-08-21 18:52:44

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2. 聚醚类抗生素K-41B、K-41A在制备治疗或预防艾滋病毒药物中的应用 [P] . 中国专利： CN111195246A . 2020-05-26

3. TREATMENT OF HIV AND AIDS USING PROBIOTIC LACTOBACILLUS REUTERI [P] . 世界知识产权组织专利： WO2010077682A2 . 2010-07-08

机译：益生性乳酸乳球菌治疗艾滋病毒和艾滋病

4. TREATMENT OF HIV AND AIDS USING PROBIOTIC LACTOBACILLUS REUTERI [P] . 世界知识产权组织专利： WO2010077682A3 . 2010-10-28

机译：益生性乳酸乳球菌治疗艾滋病毒和艾滋病

5. Use of the probiotic Strain Lactobacillus reuteri dsm17938 or a Nutritional composition comprising a probiotic bacterial Strain Lactobacillus reuteri dsm17938 because it serves to prepare a Medicine or a Nutritional composition useful to reduce Sleep disturbance and / or improve the quality of Sleep or sleep patterns in human Or animals. [P] . CL2011000891A1 . 2011-09-16

机译：益生菌罗伊氏乳杆菌dsm17938或包含益生菌罗伊氏乳杆菌dsm17938的营养组合物的用途，因为其用于制备可用于减少睡眠障碍和/或改善人的睡眠质量或睡眠模式的药物或营养组合物或动物。

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8. Analysis of Fractional-Order Deterministic HIV/AIDS Model During Drug Therapy Treatment [C] . Ajoy Dutta, Asish Adak, Praveen Kumar Gupta International Conference on Soft Computing for Problem Solving . 2020

9. Investigation of bile stress tolerance and immunomodulatory properties of probiotic Lactobacillus reuteri [D] . Whitehead, Kristi James 2009

10. Enteroadsorbent Polymethylsiloxane Polyhydrate vs. Probiotic Lactobacillus reuteri DSM 17938 in the Treatment of Rotaviral Gastroenteritis in Infants and Toddlers a Randomized Controlled Trial [O] . Leo Markovinović, Ivica Knezović, Tihana Kniewald, 2020

11. Activity of HIV Entry And Fusion Inhibitors Expressed By The Human Vaginal Colonizing Probiotic Lactobacillus Reuteri RC-14 [O] . Jiang, Yonghou, Liu, Janice, Reid, Gregor, 2007

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