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Smoking Cessation Treatment By Reducing Nicotine Cravings, Apetite Suppression, And Altering The Perceived Taste Of Tobacco Smoke

机译:通过减少尼古丁渴望,抑制磷灰石并改变烟草烟雾的感知味道来戒烟

摘要

A multi-component compound for the simultaneous treatment of nicotine addiction and the side effects of nicotine withdrawal, such as excessive appetite. The first component is a bivalent negative sulfur compound in an amount effective to control nicotine craving or the withdrawal symptoms resulting from nicotine withdrawal. The bivalent negative sulfur is selected from a group that includes, but is not limited to, alkyl sulfides, colloidal sulfur, hydropersulfides, organic thio compounds or their salts. The second component is a serotonin precursor, such as tryptophan or its derivative 5-HTP, which is used to assist the body in producing more serotonin which in turn suppresses appetite. The appetite suppressant(s) are combined with the bivalent negative sulfur compound(s) to provide a single compound that reduces nicotine craving and simultaneously suppresses increased appetite resulting from nicotine withdrawal. The compound alters the perceived taste of tobacco smoke such that it is no longer enjoyable.
机译:一种同时治疗尼古丁成瘾和尼古丁戒断副作用(如食欲不振)的多组分化合物。第一种成分是有效控制烟碱渴望或烟碱戒断所引起的戒断症状的有效量的二价负硫化合物。二价负硫选自包括但不限于烷基硫化物,胶体硫,氢过硫化物,有机硫代化合物或其盐的组。第二种成分是5-羟色胺前体,例如色氨酸或其衍生物5-HTP,用于帮助人体产生更多的5-羟色胺,进而抑制食欲。将食欲抑制剂与二价负硫化合物组合,以提供减少尼古丁渴望并同时抑制由尼古丁戒断引起的食欲增加的单一化合物。该化合物改变了人们对烟草烟雾的感觉,从而不再令人愉悦。

著录项

  • 公开/公告号US2010021570A1

    专利类型

  • 公开/公告日2010-01-28

    原文格式PDF

  • 申请/专利权人 HARLAN CLAYTON BIELEY;

    申请/专利号US20090571391

  • 发明设计人 HARLAN CLAYTON BIELEY;

    申请日2009-09-30

  • 分类号A61K31/714;A61P25/34;A61K36/84;A61K36/67;A61K36/82;

  • 国家 US

  • 入库时间 2022-08-21 18:52:45

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