首页> 外国专利> STABLE MICELLES FORMED WITH DIBLOCK COPOLYMERS OF CRITICAL MICELLE CONCENTRATION COPOLYMER AND TEMPERATURE-SENSITIVE COPOLYMER

STABLE MICELLES FORMED WITH DIBLOCK COPOLYMERS OF CRITICAL MICELLE CONCENTRATION COPOLYMER AND TEMPERATURE-SENSITIVE COPOLYMER

机译:临界胶束浓度共聚物和温度敏感型共聚物的双嵌段共聚物制成的稳定胶束

摘要

A novel class of mixed micelles formed with critical micelle concentration (Cmc) character's diblock copolymer, and temperature-sensitive character's diblock copolymer were disclosed. The mixed micelles possess complementary effects in adjusting external temperature shift (storage vs. body temperature) and concentration change (dilution after intravenous injection). The mixed micelles of the present invention can serve as a potential injectable drug delivery system for anticancer drugs, such as doxorubicin and many others.
机译:公开了具有临界胶束浓度(Cmc)特征的二嵌段共聚物和温度敏感性特征的二嵌段共聚物形成的新型混合胶束。混合的胶束在调节外部温度变化(储存与体温)和浓度变化(静脉注射后稀释)方面具有互补作用。本发明的混合胶束可以用作潜在的可注射的药物递送系统,用于抗癌药物,例如阿霉素和许多其他药物。

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