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Method for Distinguishing Follicular Thyroid Adenoma (FTA) From Follicular Thyroid Carcinoma (FTC)

机译:从滤泡性甲状腺癌(FTC)区分滤泡性甲状腺腺瘤(FTA)的方法

摘要

Follicular thyroid adenoma (FTA) is distinguished from follicular thyroid carcinoma (FTC) by comparing amount of an expression product of at least one gene selected from the group consisting of DDIT3, ARG2, ITM1, C1orf24, TARSH, and ACO1 in a test follicular thyroid specimen to a normal control thyroid specimen. The test follicular thyroid specimen is identified as FTA if the amount of expression product of TARSH is equal to or greater in the test follicular thyroid specimen than in the normal control thyroid specimen. The test follicular thyroid specimen is identified as FTC if the amount of expression product of DDIT3, ARG2, ITM1, C1orf24, or ACO1 is greater in the test follicular thyroid specimen than in the normal control thyroid specimen.
机译:甲状腺滤泡性腺瘤(FTA)与滤泡性甲状腺癌(FTC)的区别在于,在测试滤泡性甲状腺中比较了至少一种选自DDIT3,ARG2,ITM1,C1orf24,TARSH和ACO1的基因的表达产物的量标本改为正常对照甲状腺标本。如果TARSH的表达产物的量等于或大于正常对照甲状腺样品的TARSH的表达产物,则将该卵泡甲状腺样品鉴定为FTA。如果测试滤泡性甲状腺样品中DDIT3,ARG2,ITM1,C1orf24或ACO1的表达产物的量大于正常对照甲状腺样品,则将测试滤泡性甲状腺样品鉴定为FTC。

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