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Japanese encephalitis virus full-length genomic RNA, JEV cDNA having infectivity to the JEV genomic RNA, and uses thereof

机译:日本脑炎病毒全长基因组RNA,对JEV基因组RNA具有感染性的JEV cDNA及其用途

摘要

The present invention relates to a novel genomic RNA of Japanese encephalitis virus (JEV) and an infectious JEV cDNA therefrom. Particularly, the present invention relates to a full-length genomic RNA of JEV represented by SEQ. ID. No 15 and an infectious JEV cDNA therefrom. JEV genomic RNA and infectious JEV cDNA of the present invention can be used not only for the identification of the JEV genes, but also for the molecular biological studies including JEV replication, transcription, and translation. Moreover, they can also be applied to the development of the therapeutic agents, vaccines, diagnostic reagents, and diagnostic devices for Japanese encephalitis, and can be used as an expression vector for the various foreign genes.
机译:本发明涉及日本脑炎病毒(JEV)的新型基因组RNA及其传染性JEV cDNA。特别地,本发明涉及由SEQ.ID.No.1所代表的JEV的全长基因组RNA。 ID。 15号病毒,以及由此产生的传染性JEV cDNA。本发明的JEV基因组RNA和感染性JEV cDNA不仅可以用于鉴定JEV基因,而且可以用于包括JEV复制,转录和翻译的分子生物学研究。此外,它们还可以用于开发日本脑炎的治疗剂,疫苗,诊断试剂和诊断装置,并且可以用作各种外源基因的表达载体。

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