首页> 外国专利> USE OF PROTEIN 5E2 IN IN VITRO DIAGNOSIS OF LEGIONELLA PNEUMOPHILA INFECTION

USE OF PROTEIN 5E2 IN IN VITRO DIAGNOSIS OF LEGIONELLA PNEUMOPHILA INFECTION

机译:蛋白质5E2在体外诊断豚鼠嗜肺菌感染中的应用

摘要

Use of a 408 amino acid polypeptide Seq. (2) (reproduced) for in vitro detection, in biological samples, of antibodies (Ab) formed as a result of infection with Legionella pneumophila. Independent claims are included for the following: (1) similar use of (a) a functionally equivalent fragment of Seq. (2) or (b) a sequence with at least 60% identity with Seq. (2) or its fragment; (2) similar use of (a) a 1224 nt Seq. (1) (reproduced), a functionally equivalent fragment or a sequence with at least 60% identity, or a sequence complementary to any of these; (3) use of antibodies Ab1, immunospecific for Seq. (2), or its fragment or homolog, for in vitro detection of antigens of L. pneumophila; (4) kit for the new method containing at least one of the specified polypeptides, polynucleotides or antibodies and a diluent; and (5) pharmaceutical composition that contains at least one of Seq. (1) or (2), or their functional fragments, sequences with at least 60% identity or (for (Seq. (1)) complements. ACTIVITY : Antibacterial. No biological data given. MECHANISM OF ACTION : Vaccine.
机译:408个氨基酸多肽Seq。 (2)(转载)用于在生物样品中体外检测由于嗜肺军团菌感染而形成的抗体(Ab)。包括以下方面的独立权利要求:(1)(a)Seq的功能等效片段的相似用途。 (2)或(b)与Seq具有至少60%同一性的序列。 (2)或其片段; (2)(a)1224 nt Seq的类似用法。 (1)(复制的)具有至少60%同一性的功能等效片段或序列,或与这些序列中的任何一个互补的序列; (3)使用对Seq具有免疫特异性的抗体Ab1。 (2)或其片段或同源物,用于体外检测嗜肺乳杆菌的抗原; (4)用于新方法的试剂盒,其包含指定的多肽,多核苷酸或抗体中的至少一种和稀释剂; (5)药物组合物,其含有以下的至少一种。 (1)或(2)或它们的功能片段,至少具有60%同一性的序列或(对于(序列(1))互补)活性:抗菌,未提供生物学数据作用机理:疫苗。

著录项

  • 公开/公告号FR2895519B1

    专利类型

  • 公开/公告日2008-12-19

    原文格式PDF

  • 申请/专利权人 ABAG;UNIVERSITE CLAUDE BERNARD LYON 1;

    申请/专利号FR20050013416

  • 发明设计人 JEAN PHILIPPE ARIE;CAMILLE CYNCYNATUS;

    申请日2005-12-28

  • 分类号G01N33/68;C12Q1/68;C12N15/31;C07K14/195;A61K39/02;A61K38/16;A61K31/7088;A61P37/04;

  • 国家 FR

  • 入库时间 2022-08-21 19:07:35

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