首页> 外国专利> NEW ANTIPHLOGISTIC ANDROSTAN DERIVATIVES - 17-CARBOXY-LACTONE SUBSTITUTED WITH AN ARYL-CARBOXYLIC ESTER GROUP IN THE 17.ALPHA.-STELLE

NEW ANTIPHLOGISTIC ANDROSTAN DERIVATIVES - 17-CARBOXY-LACTONE SUBSTITUTED WITH AN ARYL-CARBOXYLIC ESTER GROUP IN THE 17.ALPHA.-STELLE

机译:新的抗雄激素衍生物-17-羧基内酯取代了17.Alpha.-Stelle中的芳基-羧基酯基

摘要

There are provided compounds of formula (I) wherein RSUB1 /SUBrepresents O, S or NH; RSUB2 /SUBrepresents -C(-O)-aryl or -C(-O)-heteroaryl; RSUB3 /SUBrepresents hydrogen, methyl (which may be in either the alpha or beta configuration) or methylene; RSUB4 /SUBand RSUB5 /SUBare the same or different and each represents hydrogen or halogen; and img id="CUSTOM-CHARACTER-00001" he="2.79mm" wi="7.03mm" file="US07405206-20080729-P00001.TIF" alt="custom character" img-content="character" img-format="tif"/ represents a single or a double bond; and salts and solvates thereof; process for preparing them, compositions containing them and their use in therapy.
机译:提供了式(I)化合物,其中R 1 代表O,S或NH; R 2 代表-C(-O)-芳基或-C(-O)-杂芳基; R 3 代表氢,甲基(可以为α或β构型)或亚甲基; R 4 和R 5 相同或不同,分别表示氢或卤素;和 id =“ CUSTOM-CHARACTER-00001” he =“ 2.79mm” wi =“ 7.03mm” file =“ US07405206-20080729-P00001.TIF” alt =“自定义字符” img-content =“字符” img- format =“ tif” />表示单键或双键;及其盐和溶剂化物;的制备方法,包含它们的组合物及其在治疗中的用途。

著录项

  • 公开/公告号DE60226334T2

    专利类型

  • 公开/公告日2009-06-04

    原文格式PDF

  • 申请/专利权人 GLAXO GROUP LTD.;

    申请/专利号DE2002626334T

  • 发明设计人

    申请日2002-10-17

  • 分类号C07J17;C07J31;A61K31/58;A61P5/44;A61P11/06;

  • 国家 DE

  • 入库时间 2022-08-21 19:07:55

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