DESIGNING OF CARCINOLYTIC ADENOVIRUS RECOMBINANT, SPECIFICALLY EXPRESSING IMMUNOMODULATORY FACTOR GM-CSF IN TUMORAL CELLS AND ITS APPLICATION

• 1. 肿瘤细胞专一表达免疫调节因子GM-CSF的溶瘤性腺病毒重组体的新用途 [P] . 中国专利： CN101391104B . 2010.10.06
• 2. 肿瘤细胞专一表达免疫调节因子GM－CSF的溶瘤性腺病毒重组体的新用途 [P] . 中国专利： CN101391104A . 2009-03-25
• 3. CONSTRUCTION OF ONCOLYTIC Adenovirus Recombinant Specifically Expressing Immunomodulatory Factor GM-CSF In Tumor Cells And Its Application [P] . 俄罗斯专利： RU2006146665A . 2008-07-20

  机译： 在肿瘤细胞中特异性表达免疫调节因子GM-CSF的重组腺病毒的构建及其应用

• 4. oncolytic adenovirus recombinant construct specifically expressing a gm-csf immunomodulatory factor in tumor cells and their uses [P] . BRPI0418805A . 2007-10-16

  机译： 在肿瘤细胞中特异性表达gm-csf免疫调节因子的溶瘤腺病毒重组构建体及其用途

• 5. Construction of oncolytic adenovirus recombinant that specifically expresses the GM-CSF immunomodulatory factor in tumor cells and uses thereof [P] . ES2466415T3 . 2014-06-10

  机译： 在肿瘤细胞中特异性表达GM-CSF免疫调节因子的溶瘤腺病毒重组体的构建及其用途

• 1. EFFECT ON BIOLOGICAL BEHAVIOR OF CHEMOTHERAPY-RESISTANT TUMOR CELLS BY HUMAN WILD-TYPE P53, GM-CSF AND B7-1 GENES VIA RECOMBINANT ADENOVIRUS [J] . 中国癌症研究（英文版） . 2000,第002期
• 2. Construction of hepatocyte growth factor gene recombinant adenovirus vector and its expression in rat bone marrow mesenchymal stem cells [J] . Yue Yu, Feng Zhang, Ling Lü, 生物医学研究杂志（英文版） . 2008,第002期
• 3. Overexpression of TIMP-1 mediated by recombinant adenovirus in hepatocellular carcinoma cells inhibits proliferation and invasion in vitro [J] . Dong Xia, Lu-Nan Yan, Jian-Guo Xie, 国际肝胆胰疾病杂志（英文版） . 2006,第003期
• 4. Efficacy of recombinant adenovirus expressing a fusion gene from GM-CSF and Epstein-Barr virus LMP2A in a mouse tumor model [J] . Xue Qingjie, Li Xiuzhen, Yang Chunqing, Human vaccines & immunotherapeutics. . 2017,第10期
• 5. EFFECT ON BIOLOGICAL BEHAVIOR OF CHEMOTHERAPY- RESISTANT TUMOR CELLS BY HUMAN WILD-TYPE p53, GM-CSF AND B7-1 GENES VIA RECOMBINANT ADENOVIRUS [J] . FAN Guo-change, WU Zu-ze, WANG Yan-fei Chinese Journal of Cancer Research . 2000,第2期
• 6. Granulocyte Macrophage-Colony Stimulating Factor (GM-CSF) Downregulates the Expression of Protumor Factors Cyclooxygenase-2 and Inducible Nitric Oxide Synthase in a GM-CSF Receptor-Independent Manner in Cervical Cancer Cells [J] . NanyanJiang, ZhiqiangTian, JunTang, Mediators of inflammation . 2015,第6期
• 7. Protection induced by a recombinant replication-defective adenovirus vaccine expressing the P97 protein o￡ Mycoplasma byopneumoniae in challenged pigs: Comparison to Suvaxyn~R MH-one vaccine [C] . E R. Okamba, M. Arella, N. Music, Annual Meeting of the American Association of Swine Veterinarians . 2009
• 8. Tumorigenic adenovirus 12 cells evade NK lysis by reducing the expression of NKG2D ligands [D] . Heyward, Christa Y. 2011
• 9. Efficacy of recombinant adenovirus expressing a fusion gene from GM-CSF and Epstein-Barr virus LMP2A in a mouse tumor model [O] . Qingjie Xue, Xiuzhen Li, Chunqing Yang, 2017
• 10. Granulocyte Macrophage-Colony Stimulating Factor (GM-CSF) Downregulates the Expression of Protumor Factors Cyclooxygenase-2 and Inducible Nitric Oxide Synthase in a GM-CSF Receptor-Independent Manner in Cervical Cancer Cells [O] . Nanyan Jiang, Zhiqiang Tian, Jun Tang, 2015
• 11. Targeted Tumor Therapy by Use of Recombinant Adenovirus Vectors That Selectively Replicate in Hypoxic Regions of Tumors. [R] . Li, C. Y., Huang, Q., Dewhirst, M. W. 2003

• 1. Synergetic anticancer effect of combined quercetin and recombinant adenoviral vector expressing human wild-type p53,GM-CSF and B7-1 genes on hepatocellular carcinoma cells in vitro [J] . MingShi ,Fu-ShengWang ,Zu-ZeWu . 世界胃肠病学杂志：英文版 . 2003,第1期
• 2. The construction and expression of human GM-CSF recombinant adenovirus vector [J] . Hirofumi Hamada . 中国实验血液学杂志 . 1997,第3期
• 3. 癌症病人术后主动特异性免疫治疗(ASI)——NDV修饰自体肿瘤细胞疫苗主动特异性免疫治疗的理论基础 [C] . 韩小红 ,李刚毅 . 中国抗癌协会临床肿瘤学协作中心第五届学术年会 . 2001
• 4. 2810430M08Rik基因的组织特异性表达及在T淋巴细胞免疫反应中的作用 [A] . 吴涛 . 2007