首页> 外国专利> Compositions for increasing the enzymatic activity of LIPG polypeptide and lowering the levels of very low density lipoproteinVLDL cholesterol and low density lipoproteinLDL cholesterol and a method for identifying a compound useful for the same

Compositions for increasing the enzymatic activity of LIPG polypeptide and lowering the levels of very low density lipoproteinVLDL cholesterol and low density lipoproteinLDL cholesterol and a method for identifying a compound useful for the same

机译:用于提高LIPG多肽的酶促活性并降低极低密度脂蛋白VLDL胆固醇和低密度脂蛋白LDL胆固醇的水平的组合物以及用于该化合物的化合物的鉴定方法

摘要

Compositions and methods for raising the level of HDL cholesterol and apolipoprotein AI in a patient and for lowering the levels of VLDL cholesterol and LDL cholesterol in a patient, including compositions and methods which effect the expression of a gene, LIPG, which encodes a lipase enzyme that is a member of the tryacylglycerol lipase family or which effect the enzymatic activity of the enzyme.
机译:用于提高患者中HDL胆固醇和载脂蛋白AI水平以及降低患者VLDL胆固醇和LDL胆固醇水平的组合物和方法,包括影响编码脂肪酶的基因LIPG表达的组合物和方法它是三酰基甘油脂肪酶家族的成员,或影响该酶的酶促活性。

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