首页> 外国专利> NOVEL 3-CHLORO-5-SUBSTITUTED-QUINOXALINE-2-AMINE DERIVATIVES AND PHARMACEUTICALLY ACCEPTABLE SALT THEREOF, METHOD FOR PREPARATION, THERAPEUTIC AGENT FOR ANTIINFLAMMATORY DISEASE INDUCED BY SPC ACTIVITY CONTAINING 3-CHLORO-5-SUBSTITUTED-QUINOXALINE-2-AMINE DERIVATIVES AS AN EFFECTIVE INGREDIENT

NOVEL 3-CHLORO-5-SUBSTITUTED-QUINOXALINE-2-AMINE DERIVATIVES AND PHARMACEUTICALLY ACCEPTABLE SALT THEREOF, METHOD FOR PREPARATION, THERAPEUTIC AGENT FOR ANTIINFLAMMATORY DISEASE INDUCED BY SPC ACTIVITY CONTAINING 3-CHLORO-5-SUBSTITUTED-QUINOXALINE-2-AMINE DERIVATIVES AS AN EFFECTIVE INGREDIENT

机译：新型3-氯5-取代的喹诺啉2-胺衍生物及其药学可接受的盐，其制备方法，包含3-氯5-取代的喹诺酮类药物的SPC活性引起的抗炎性疾病的治疗剂。有效成分

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摘要

Provided is a 3-chloro-5-substituted-quinoxaline-2-amine derivative and a therapeutic agent using the 3-chloro-5-substituted-quinoxaline-2-amine derivative so as to treat diseases associated with inflammation. A 3-chloro-5-substituted-quinoxaline-2-amine derivative is represented by the formula 1. In the formula 1, R1 indicates hydrogen, linear or branched C1-C10 alkyl group, C1-C10 alkoxy group or halogen; R2 shows linear or branched C1-C10 alkyl group, C1-C10 alkoxy group, hydroxyl group, halogen group, amine group or substituted amine group, amide group, carbamate group or urea group. In the formula 1, the substituted group indicates a substituted phenyl group wherein one or four groups selected from the group consisting of a linear or branched C1-C10 alkyl group, halogen, nitro group, C1-C10 alkyl group, C1-C10 alkoxy group and C1-C10 haloalkyl group are substituted.

机译：提供3-氯-5-取代-喹喔啉-2-胺衍生物和使用3-氯-5-取代-喹喔啉-2-胺衍生物的治疗剂，以治疗与炎症有关的疾病。 3-氯-5-取代的喹喔啉-2-胺衍生物由式1表示。式1中，R 1表示氢，直链或支链的C 1 -C 10烷基，C 1 -C 10烷氧基或卤素。 R 2表示直链或支链的C 1 -C 10烷基，C 1 -C 10烷氧基，羟基，卤素基，胺基或取代的胺基，酰胺基，氨基甲酸酯基或脲基。在式1中，取代基表示取代苯基，其中选自直链或支链C1-C10烷基，卤素，硝基，C1-C10烷基，C1-C10烷氧基的一个或四个基团。 C1-C10卤代烷基被取代。

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公开/公告号KR20090032373A

专利类型
公开/公告日2009-04-01

原文格式PDF
申请/专利权人 KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY;AMOREPACIFIC CORPORATION;
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申请/专利号KR20070097554
发明设计人 GONG YOUNG DAE;CHO HEE YEONG;JEON MOON KOOK;LEE TAE HO;CHOI GIL DON;KONG JAE YANG;PARK WOO KYU;HWANG SOON HEE;KIM JUNG JU;LEE CHANG HOON;KO JAE YOUNG;NOH MIN SOO;HAN EUN SIL;KIM HYUK;YUN JUN WON;MOH JOO HYUN;KIM DO HOON;
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申请日2007-09-27
分类号C07D401/12;A61K31/498;A61P29;
国家 KR
入库时间 2022-08-21 19:13:42

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